There are several diverse mechanisms of antibiotic resistance in B. pseudomallei, which includes multi-drug efflux pumps [5,six], enzymatic inactivation [seven,8], impermeability of the bacterial mobile membrane [9] and mutations in the antibiotic focus on site [ten]

Burkholderia pseudomallei, the etiologic agent of melioidosis, is a saprophytic bacterium that is typically identified in surface waters and soil of Australia and Thailand. There is no successful vaccine from…