DDX18 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 625 and the C-terminus (residue 670) of human DEAD (Asp-Glu-Ala-Asp) Box Protein 18 using the numbering given in entry NP_006764.3 (GeneID 8886).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
DDX18
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Positive Control |
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| Publications |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
TBS and 0.1% BSA
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| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for DDX18 Antibody
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
- DEAD box protein 18
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated)
- EC 3.6.1
- EC 3.6.4.13
- FLJ33908
- MrDbATP-dependent RNA helicase DDX18
- Myc-regulated DEAD box protein
Background
DDX18 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX18 has been observed to be a target of myc-max heterodimers. Alternate names for DDX18 include ATP-dependent RNA helicase DDX18, DEAD box protein 18, myc-regulated DEAD box protein, and MrDb.