Luminal space in the microperfused pancreatic ducts. Conclusion: These findings indicate that the fluid and bicarbonate secretion is substantially improved inside the absence of serotonin,which could possibly contribute to the decreased severity of AP in TPH knockout mice. LCB14-0602 web Disclosure of Interest: None declaredA hours.The mortality was only . within this group,nevertheless,it was improved by occasions among these sufferers who PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26663416 either much more or significantly less fluid. With regards to the enteral feeding, of patients with severe pancreatitis didn’t receive it. The mortality price within this group was unacceptably high compared to those sufferers who the correct remedy( Conclusion: Appropriate utilization with the IAPAPA EBM guidelines could save a huge number of lives. It is actually vitally vital to make the suggestions obtainable in all languages of the countries. Disclosure of Interest: None declaredP EARLY DIFFERENTIAL DIAGNOSIS OF PANCREATITIS FROM A lot more Severe FORMSMILDACUTEA. I. Ershova,,A. V. Popov,,D. A. Mineev,N. N. Popova Hospital surgery,Perm State Healthcare University,Laboratory of Physical hydrodynamics,Institute of Continuous Media Mechanics,Ural Branch of Russian Academy of Science,Basic Surgery,Perm State Medical University,Perm,Russian Federation Get in touch with Email Address: ershovaainbox.ru Introduction: Acute pancreatitis (AP) is characterized by a wide selection of clinical courses,varying from interstitial edema to pancreatic necrosis. This determines the relevance of very simple and rapid criteria for early detection in the disease severity. Aims Methods: The aim would be to establish the effectiveness of rating scales for early stratification of AP. The severity of patient’s situation was estimated in hours using the help of such rating scales as BISAP,HAPS,SOFA,SIRS,US scale . The severity of AP was detected in accordance with the classification of Atlanta in hours. BalthazarRanson scale was used in the same time period. ROCanalysis with the scales was performed together with the calculation of the region beneath the operating characteristic curve (AUC). Benefits: There were patients with AP (mean age . . male),of which . have been classified as mild. as moderate . as serious. Determination of mild AP as outlined by the BISAP h US scale was characterized by higher accuracy (AUC ( self-confidence interval) . . respectively),sensitivity. respectively) and negative predictive worth. respectively). The scales HAPS ,SOFA and SIRS had smaller AUC (p) ( . respectively),lower high-quality of determining of mild AP ( . sensitivity respectively). Additionally they had smaller negative predictive worth ( . respectively). Conclusion: The BISAP scale and US scale are trusted strategies for early detection of mild AP (in hours). Their higher constructive prognostic values. permit to recognize on early stage the patients which might be not needed intensive care. This could save substantial costs for the hospital. References . Popov Ershova AV,Mineev A. I.D. A et al. Validation of the original ultrasound scale for stratification of severity of acute pancreatitis. UEG journal ; : A. . This operate was supported by a grant from the Russian Science Foundation ,,. Disclosure of Interest: None declaredP Important Significance In the DISSEMINATION OF IAPAPA Recommendations: DRAMATIC Final results Throughout the VALIDATION STUDY ON A NATIONWIDE COHORT A. Parniczky,,I. Hritz,A. Balazs,S. Godi,A. Halasz,B. Kui,D. Mosztbacher,A. Szu cs,J. Sumegi,B. Bod,J. Novak,S. Crai,J. Hamvas ,T. Kiss ,M. Varga ,K. Csefko ,P. Sarlos ,J. Bajor,I. Szabo,F. Izbeki,J. Gervain,T. Takacs,L. Czako,Z. Szepes,R. Bor,V.