steady two Proton-NMR spectra of the MGP esters 20 three 4 5 six 7 8 9 ten 5.63 (1H, d, J eight.0)Compounds (chemical shifts, ppm, Hz)ProtonsH-H-6aH-6bGlycoconjugate Journal (2022) 39:261H-4.40 (1H, dd, J 11.1 and six.6) four.20 (1H, dd, J 11.2 and six.eight) 4.65 (1H, d, J 3.7)H-H-4.96 (1H, d, J eight.0) 4.85 (1H, dd, J 11.1 and six.5) 4.72 (1H, dd, J 11.1 and 6.7) four.22 (1H, d, J three.five) four.09 (1H, dd, J 3.0 and 10.5) three.88 (1H, dd, J eight.0 and ten.five) three.58 (1H, m) 3.36 (3H, s) 2.38 (2H, m) 1.64 (2H, m) 1.25 (20H, m) 0.96 (3H, m) two.21, 2.14, 2.11 (3 3H, three s) two.36 (6H, m) 1.68 (6H, m) 0.98 (3H, m) two.31 (6H, m) 1.24 (78H, m) 0.91 (9H, m) 0.96 (3H, m) 0.94 (3H, m) 0.93 (3H, m) 1.28 (20H, m) 1.26 (20H, m) 1.32 (20H, m) 1.24 (20H, m) 0.91 (3H, m) 1.25 (20H, m) 0.88 (3H, m) 1.27 (20H, m) 0.98 (3H, m)four.94 (1H, d, J 8.0) 4.11 (1H, dd, J 11.2 and 6.six) three.94 (1H, dd, J 11.2 and six.eight) 4.68 (1H, d, J three.five) four.74 (1H, dd, J 3.3 and ten.7) 4.81 (1H, dd, J 8.0 and ten.4) three.88 (1H, m) 3.45 (3H, s) two.36 (2H, m) 1.68 (2H, m)5.41 (1H, d, J eight.two) four.22 (1H, dd, J 11.1 and 6.eight) 4.16 (1H, dd, J 11.0 and six.8) 4.46 (1H, d, J 3.5 five.13 (1H, dd, J three.2 and 10.6) five.21 (1H, dd, J eight.1 and 10.5) three.92 (1H, m) 3.45 (3H, s) 2.35 (2H, m) 1.66 (2H, m)five.38 (1H, d, J 8.three) four.39 (1H, dd, J 11.two and six.7) four.14 (1H, dd, J 11.0 and six.7) four.75 (1H, d, J three.6) five.03 (1H, dd, J three.1 and 10.six) five.16 (1H, dd, J eight.0 and 10.five) 3.99 (1H, m) 3.47 (3H, s) two.34 (2H, m) 1.64 (2H, m)five.30 (1H, d, J 8.1) four.40 (1H, dd, J 11.two and 6.6) four.11 (1H, dd, J 11.two and six.eight) 4.85 (1H, d, J 3.7) five.01 (1H, dd, J 3.two and 10.six) five.15 (1H, dd, J 8.two and ten.six) 3.51 (1H, m) 3.45 (3H, s) two.31 (2H, m) 1.62 (2H, m)5.22 (1H, d, J 8.0) four.30 (1H, dd, J 11.1 and 6.six) four.10 (1H, dd, J 11.0 and 6.7) 4.55 (1H, d, J three.6) four.75 (1H, dd, J 3.0 and ten.6) 5.05 (1H, dd, J eight.1 and ten.six) 3.91 (1H,m) 3.56 (3H, s) 2.32 (2H, m) 1.61 (2H, m)5.48 (1H, d, J 8.two) four.40 (1H, dd, J 11.two and six.6) four.01 (1H, dd, J 11.2 and 6.8) 4.66 (1H, d, J three.7) 5.05 (1H, dd, J three.2 and 10.6) 5.34 (1H, dd, J 8.2 and 10.six) 3.52 (1H, m) 3.50 (3H, s) two.33 (2H, m) 1.63 (2H, m)five.23 (1H, d, J 8.1) four.27 (1H, dd, J 11.0 and six.5) four.11 (1H, dd, J 11.1 and 6.9) four.53 (1H, d, J three.5) 4.77 (1H, dd, J 3.1 and 10.5) 5.08 (1H, dd, J eight.0 and 10.five) three.98 (1H, m) three.46 (3H, s) two.37 (2H, m) 1.63 (2H, m)5.01 (1H, dd, J 3.0 and ten.five) five.21 (1H, dd, J 8.2 and ten.six) 4.00 (1H, m) three.46 (3H, s) 2.35 (2H, m) 1.65 (2H, m) 1.24 (20H, m) 0.86 (3H, m)1.28 (20H, m)H-5 1-OCH3 CH3(CH2)11CH2CO CH3(CH2)10CH2CH 2CO CH3(CH2)10CH2CH 2CO CH3(CH2)12CO three CH3CO0.94 (3H, m)three CH3CH2CH2CO 3 CH3CH2CH2CO 3 CH3(CH2)2CO three CH3(CH2)13CH2CO 3 CH3(CH2)13CH2CO three CH3(CH2)14CO 3 CH3(CH2)15CH2CO 3 CH3(CH2)15CH2CO 3 CH3(CH2)1 three Ar2.27 (6H, m) 1.29 (90H, m) 0.90 (9H, m)3 PhCH = CHCO7.67 (18H, m) 7.45 (27H, m)7.54 (6H, m) 7.28 (9H, m) 7.75 7.52, 7.37 (3 1H, 3 d, J 16.8.03 (6H, m) 7.94 (6H, m)Glycoconjugate Journal (2022) 39:261and are presented in Table four, Figs. 6, 7. The compounds showed D2 Receptor web promising inhibitory activity against many both Gram-positive and Gram-negative bacteria. The inhibition data (Table four) indicated that compound 4 showed the highest activity (39 0.4 mm); compounds two (29 0.4 mm), 3 (21 0.three mm), eight (25 0.3 mm), and ten (34 0.4 mm) were also exhibited a superb inhibition activity against Bacillus subtilis than the standard antibiotic azithromycin (19 0.three mm). However, compound 10 (26 0.three mm) showed much more activity than regular drug on Staphylococcus ErbB3/HER3 Purity & Documentation aureus. On the other hand, compounds 3 (20 0.three mm), 4 (22 0.three mm), six (20 0.3 mm), 7 (18 0.three mm), and 10 (3