Product Name :
Tenofovir-C3-O-C15-CF3 ammonium
Description:
Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
CAS:
2611373-80-7
Molecular Weight:
640.72
Formula:
C28H52F3N6O5P
Chemical Name:
ammonium 3-[(16, 16, 16-trifluorohexadecyl)oxy]propyl ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
Smiles :
[NH4+].C[C@H](CN1C=NC2=C(N)N=CN=C12)OC[P@]([O-])(=O)OCCCOCCCCCCCCCCCCCCCC(F)(F)F
InChiKey:
MAVYHINXUMVIRW-GJFSDDNBSA-N
InChi :
InChI=1S/C28H49F3N5O5P.H3N/c1-24(20-36-22-35-25-26(32)33-21-34-27(25)36)40-23-42(37,38)41-19-15-18-39-17-14-12-10-8-6-4-2-3-5-7-9-11-13-16-28(29,30)31;/h21-22,24H,2-20,23H2,1H3,(H,37,38)(H2,32,33,34);1H3/t24-;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Amrubicin} MedChemExpress|{Amrubicin} Cell Cycle/DNA Damage|{Amrubicin} Purity & Documentation|{Amrubicin} Formula|{Amrubicin} manufacturer|{Amrubicin} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Trastuzumab duocarmazine} web|{Trastuzumab duocarmazine} Antibody-drug Conjugate/ADC Related|{Trastuzumab duocarmazine} Technical Information|{Trastuzumab duocarmazine} References|{Trastuzumab duocarmazine} supplier|{Trastuzumab duocarmazine} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24428212
Additional information:
Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.|Product information|CAS Number: 2611373-80-7|Molecular Weight: 640.72|Formula: C28H52F3N6O5P|Chemical Name: ammonium 3-[(16, 16, 16-trifluorohexadecyl)oxy]propyl ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate|Smiles: [NH4+].C[C@H](CN1C=NC2=C(N)N=CN=C12)OC[P@]([O-])(=O)OCCCOCCCCCCCCCCCCCCCC(F)(F)F|InChiKey: MAVYHINXUMVIRW-GJFSDDNBSA-N|InChi: InChI=1S/C28H49F3N5O5P.H3N/c1-24(20-36-22-35-25-26(32)33-21-34-27(25)36)40-23-42(37,38)41-19-15-18-39-17-14-12-10-8-6-4-2-3-5-7-9-11-13-16-28(29,30)31;/h21-22,24H,2-20,23H2,1H3,(H,37,38)(H2,32,33,34);1H3/t24-;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.Products are for research use only. Not for human use.|