Product Name :
(S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride
Description:
(S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC. (S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.
CAS:
2376990-26-8
Molecular Weight:
632.64
Formula:
C28H43Cl2N5O5S
Chemical Name:
(2S, 4R)-N-{[2-(4-aminobutoxy)-4-(4-methyl-1, 3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-2-acetamido-3, 3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Smiles :
Cl.Cl.CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCN)C1SC=NC=1C)C(C)(C)C
InChiKey:
LDWASNPVOMODPJ-OTCWRJAQSA-N
InChi :
InChI=1S/C28H41N5O5S.{{Oclacitinib} MedChemExpress|{Oclacitinib} JAK/STAT Signaling|{Oclacitinib} Biological Activity|{Oclacitinib} References|{Oclacitinib} manufacturer|{Oclacitinib} Epigenetic Reader Domain} 2ClH/c1-17-24(39-16-31-17)19-8-9-20(23(12-19)38-11-7-6-10-29)14-30-26(36)22-13-21(35)15-33(22)27(37)25(28(3,4)5)32-18(2)34;;/h8-9,12,16,21-22,25,35H,6-7,10-11,13-15,29H2,1-5H3,(H,30,36)(H,32,34);2*1H/t21-,22+,25-;;/m1../s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ensitrelvir} MedChemExpress|{Ensitrelvir} Virus Protease|{Ensitrelvir} Purity & Documentation|{Ensitrelvir} In stock|{Ensitrelvir} supplier|{Ensitrelvir} Epigenetics}
Shelf Life:
≥12 months if stored properly.PMID:33300466
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC. (S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.|Product information|CAS Number: 2376990-26-8|Molecular Weight: 632.64|Formula: C28H43Cl2N5O5S|Synonym:|VH032-phenol-C4-NH2 dihydrochloride|Chemical Name: (2S, 4R)-N-{[2-(4-aminobutoxy)-4-(4-methyl-1, 3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-2-acetamido-3, 3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide dihydrochloride|Smiles: Cl.Cl.CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCN)C1SC=NC=1C)C(C)(C)C|InChiKey: LDWASNPVOMODPJ-OTCWRJAQSA-N|InChi: InChI=1S/C28H41N5O5S.2ClH/c1-17-24(39-16-31-17)19-8-9-20(23(12-19)38-11-7-6-10-29)14-30-26(36)22-13-21(35)15-33(22)27(37)25(28(3,4)5)32-18(2)34;;/h8-9,12,16,21-22,25,35H,6-7,10-11,13-15,29H2,1-5H3,(H,30,36)(H,32,34);2*1H/t21-,22+,25-;;/m1../s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|