Product Name :
XL147 analogue

CAS No.:
956958-53-5

Purity :
> 98%

Shipping:
Shipped on dry ice.

Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month

SMILES:
CC1=CC=C(C=C1)[S](=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4

Product Description :
XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.

Formula:
C21H16N6O2S2

Molecular Weight :
448.{{2519537-70-1} MedChemExpress|{2519537-70-1} Purity & Documentation|{2519537-70-1} In Vitro|{2519537-70-1} manufacturer} 52

Synonyms:
SAR245408

Additional Information:
|CAS No.{{1970972-74-7} site|{1970972-74-7} Biological Activity|{1970972-74-7} Data Sheet|{1970972-74-7} manufacturer} 956958-53-5 ; |Synonyms SAR245408 ; |Formula C21H16N6O2S2 ; |Molecular Weight 448.PMID:30725699 52 ; |SMILES CC1=CC=C(C=C1)[S](=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4 ; |Target PI3Kβ ; |Product Description XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO

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