Product Name :
DBCO-Maleimide
Description:
DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
1395786-30-7
Molecular Weight:
427.45
Formula:
C25H21N3O4
Chemical Name:
N-(3-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
Smiles :
O=C(CCNC(=O)CCN1C(=O)C=CC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12
InChiKey:
NHFQNAGPXIVKND-UHFFFAOYSA-N
InChi :
InChI=1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 1395786-30-7|Molecular Weight: 427.45|Formula: C25H21N3O4|Chemical Name: N-(3-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide|Smiles: O=C(CCNC(=O)CCN1C(=O)C=CC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12|InChiKey: NHFQNAGPXIVKND-UHFFFAOYSA-N|InChi: InChI=1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (292.{{C 87} MedChemExpress|{C 87} TNF Receptor|{C 87} Purity & Documentation|{C 87} Formula|{C 87} supplier|{C 87} Autophagy} 43 mM; ultrasonic and warming and heat to 60°C).{{Phenacetin} web|{Phenacetin} COX|{Phenacetin} Purity & Documentation|{Phenacetin} In stock|{Phenacetin} manufacturer|{Phenacetin} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32432445 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|