Product: Clorgiline (hydrochloride)
SNX26 Antibody Summary
Immunogen |
Peptide with sequence SWSLHSEGQTRSYC corresponding to C-Terminus according to NP_443180.2.
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Clonality |
Polyclonal
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Host |
Goat
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Gene |
ARHGAP33
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Purity |
Immunogen affinity purified
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Applications/Dilutions
Dilutions |
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Application Notes |
WB: Preliminary experiments gave an approx. 75 kDa band in human bone marrow, kidney, and pancreas lysates after 1 ug/ml antibody staining. EB05916 may detect the isoform A1A5D2 (UniProtKB) with a molecular weight of 81.4 kDa band which is similar in amino acid sequence to NP_443180.2 however lacking aa729-1268. Please note that currently we cannot find a precise explanation in the literature for the band we observe given the calculated size of 121 kDa band according to NP_443180.2. The 75 kDa band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human brain shows cytoplasm staining of Purkinje cells in cerebellum.
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Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse.
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles.
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Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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Preservative |
0.02% Sodium Azide
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Concentration |
0.5 mg/ml
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Purity |
Immunogen affinity purified
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Alternate Names for SNX26 Antibody
- FLJ39019
- neurite outgrowth multiadaptor RhoGAP protein
- NOMA-GAP
- Rho GTPase activating protein 33
- rho GTPase-activating protein 33
- Rho-type GTPase-activating protein 33
- sorting nexin 26
- Sorting nexin-26
- Tc10/CDC42 GTPase-activating protein
- TCGAPSNX26
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.