Product: LF3

MAP4K6 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from internal region of human MINK1 / MAP4K6.
Specificity
Human MINK1 / MAP4K6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Opossum (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
MINK1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.6 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MAP4K6 Antibody

  • B55
  • EC 2.7.11
  • GCK family kinase MiNK
  • hMINK
  • hMINKbeta
  • MAP4K6EC 2.7.11.1
  • MAPK/ERK kinase kinase kinase 6
  • MEK kinase kinase 6
  • MGC21111
  • MINKMEKKK 6
  • Misshapen/NIK-related kinase
  • misshapen-like kinase 1 (zebrafish)
  • misshapen-like kinase 1
  • Mitogen-activated protein kinase kinase kinase kinase 6
  • serine/threonine protein kinase
  • YSK2
  • ZC3

Background

MINK is a MSN type protein kinase. The protein has a structure similar to other germinal center kinases, and it has been shown to activate the c-Jun N-terminal kinase and p38 pathways.

PMID: 10548277

Product: Naproxen

MAP4K6 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 575 and 625 of human misshapen-like kinase 1 using the numbering given in entry NP_722549.2 (GeneID 50488).
Predicted Species
Rat (100%), Porcine (100%), Primate (100%), Monkey (100%), Guinea Pig (100%), Canine (100%), Equine (100%), Rabbit (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
MINK1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Panda, Rhesus Monkey, Gorilla, Chimpanzee, Tasmanian devil, White-tufted-ear marmoset, Crab-eating macaque, European domestic ferret and Northern white-cheeked gibbon.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MAP4K6 Antibody

  • B55
  • EC 2.7.11
  • GCK family kinase MiNK
  • hMINK
  • hMINKbeta
  • MAP4K6EC 2.7.11.1
  • MAPK/ERK kinase kinase kinase 6
  • MEK kinase kinase 6
  • MGC21111
  • MINKMEKKK 6
  • Misshapen/NIK-related kinase
  • misshapen-like kinase 1 (zebrafish)
  • misshapen-like kinase 1
  • Mitogen-activated protein kinase kinase kinase kinase 6
  • serine/threonine protein kinase
  • YSK2
  • ZC3

Background

MINK1 (misshapen/NIKs-related kinase 1) is a member of the germinal center kinase (GCK) family that are homologous to the yeast sterile 20 (Ste20) kinases. GCKs function in the activation of the JNK pathway. MINK1 has been found to activate the JNK pathway and may have a role in modulating cytoskeletal organization, cell adhesion, and cell migration during development.

PMID: 22265413

Related Post