Product: IQ-1

PAK6 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from N-terminus of human PAK6.
Specificity
Human PAK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PAK7 (69%).
Predicted Species
Xenopus (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
PAK6
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10 – 1:500
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Gorilla, Orangutan, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Sparrow (100%), Platypus (100%), Goat (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAK6 Antibody

  • EC 2.7.11
  • p21 protein (Cdc42/Rac)-activated kinase 6
  • p21(CDKN1A)-activated kinase 6
  • p21-activated kinase 6
  • p21-activated protein kinase 6
  • PAK-5
  • PAK5EC 2.7.11.1
  • PAK6
  • PAK-6
  • serine/threonine-protein kinase PAK 6

Background

PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac; however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha.

PMID: 24282028

Related Post