UVRAG Antibody Summary
| Immunogen |
This antibody is specific for the C Terminus Region of the target protein.
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| Specificity |
This product is specific for Human UVRAG.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
UVRAG
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA and Western Blot.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for UVRAG Antibody
- beclin 1 binding protein
- DHTX
- disrupted in heterotaxy
- p63
- UV radiation resistance associated gene
- UV radiation resistance-associated gene protein
- UVRAG
- VPS38
Background
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq]