E. Part of his explanation for the error was his willingness to capitulate when tired: `I did not ask for any medical history or something like that . . . more than the phone at 3 or 4 o’clock [in the morning] you simply say yes to anything’ pnas.1602641113 Interviewee 25. Despite sharing these similar traits, there were some differences in error-producing circumstances. With KBMs, physicians had been conscious of their know-how deficit at the time in the prescribing choice, unlike with RBMs, which led them to take among two pathways: approach other individuals for314 / 78:2 / Br J Clin PharmacolLatent conditionsSteep hierarchical structures within health-related teams prevented medical doctors from searching for assist or indeed receiving adequate assist, highlighting the value with the prevailing health-related culture. This varied among specialities and accessing advice from seniors appeared to become more problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for advice to prevent a KBM, he felt he was annoying them: `Q: What produced you think which you may be annoying them? A: Er, just because they’d say, you know, very first words’d be like, “Hi. Yeah, what is it?” you know, “I’ve scrubbed.” That’ll be like, sort of, the introduction, it would not be, you know, “Any issues?” or something like that . . . it just does not sound extremely approachable or friendly around the telephone, you know. They just sound rather direct and, and that they have been busy, I was inconveniencing them . . .’ Interviewee 22. Medical culture also influenced doctor’s behaviours as they acted in strategies that they felt have been required to be able to fit in. When exploring doctors’ reasons for their KBMs they discussed how they had chosen not to seek tips or info for worry of hunting incompetent, specially when new to a ward. Interviewee two below explained why he didn’t verify the dose of an antibiotic in spite of his uncertainty: `I knew I should’ve looked it up cos I did not really know it, but I, I think I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was one thing that I should’ve identified . . . because it is extremely quick to have caught up in, in getting, you know, “Oh I’m a Physician now, I know stuff,” and using the stress of individuals who are maybe, kind of, a little bit more senior than you considering “what’s wrong with him?” ‘ Interviewee two. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent condition in lieu of the actual culture. This interviewee discussed how he eventually discovered that it was acceptable to verify info when prescribing: `. . . I PNPPMedChemExpress PNPP locate it rather nice when Consultants open the BNF up within the ward rounds. And also you assume, nicely I am not supposed to know every Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone cancer single medication there’s, or the dose’ Interviewee 16. Health-related culture also played a part in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior physicians or experienced nursing staff. A great example of this was provided by a physician who felt relieved when a senior colleague came to help, but then prescribed an antibiotic to which the patient was allergic, regardless of possessing currently noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and said, “No, no we need to give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it on the chart without the need of pondering. I say wi.E. A part of his explanation for the error was his willingness to capitulate when tired: `I did not ask for any health-related history or anything like that . . . over the telephone at three or four o’clock [in the morning] you simply say yes to anything’ pnas.1602641113 Interviewee 25. Despite sharing these related characteristics, there had been some differences in error-producing circumstances. With KBMs, medical doctors have been aware of their expertise deficit at the time of your prescribing decision, unlike with RBMs, which led them to take one of two pathways: approach other individuals for314 / 78:two / Br J Clin PharmacolLatent conditionsSteep hierarchical structures within medical teams prevented doctors from searching for support or indeed receiving sufficient assistance, highlighting the significance on the prevailing medical culture. This varied involving specialities and accessing assistance from seniors appeared to become additional problematic for FY1 trainees functioning in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for tips to stop a KBM, he felt he was annoying them: `Q: What created you believe which you could be annoying them? A: Er, just because they’d say, you understand, initially words’d be like, “Hi. Yeah, what exactly is it?” you know, “I’ve scrubbed.” That’ll be like, kind of, the introduction, it wouldn’t be, you know, “Any complications?” or something like that . . . it just doesn’t sound pretty approachable or friendly around the phone, you know. They just sound rather direct and, and that they have been busy, I was inconveniencing them . . .’ Interviewee 22. Health-related culture also influenced doctor’s behaviours as they acted in approaches that they felt had been essential as a way to match in. When exploring doctors’ reasons for their KBMs they discussed how they had selected not to seek suggestions or information and facts for fear of hunting incompetent, in particular when new to a ward. Interviewee two below explained why he didn’t check the dose of an antibiotic despite his uncertainty: `I knew I should’ve looked it up cos I didn’t actually know it, but I, I feel I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was anything that I should’ve identified . . . since it is extremely straightforward to acquire caught up in, in being, you understand, “Oh I’m a Medical doctor now, I know stuff,” and with the pressure of persons that are perhaps, sort of, a little bit more senior than you thinking “what’s wrong with him?” ‘ Interviewee two. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent situation in lieu of the actual culture. This interviewee discussed how he at some point learned that it was acceptable to verify information when prescribing: `. . . I find it fairly nice when Consultants open the BNF up within the ward rounds. And you consider, nicely I’m not supposed to know each and every single medication there is, or the dose’ Interviewee 16. Medical culture also played a function in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior physicians or experienced nursing staff. A very good instance of this was given by a medical doctor who felt relieved when a senior colleague came to assist, but then prescribed an antibiotic to which the patient was allergic, despite obtaining already noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and mentioned, “No, no we should really give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it on the chart with out thinking. I say wi.