Und I, Sing A, Naslund J: Is Placebo Acupuncture What It
Und I, Sing A, Naslund J: Is Placebo Acupuncture What It is Intended to Be? Evid Based Complement Alternat Med 2011, 932407. Tian JH, Zhang W, Fang Y, Xu W, Grandy DK, Han JS: Endogenous orphanin FQ: evidence for a role in the modulation of electroacupuncture analgesia and the development of tolerance to analgesia produced by morphine and electroacupuncture. Br J Pharmacol 1998, 124:21?6. Ulett GA, Han S, Han JS: Electroacupuncture: mechanisms and clinical application. Biol Psychiatry 1998, 44:129?38.doi:10.1186/1749-8546-7-17 Cite this article as: Aguiar et al.: Electroacupuncture at the ST36 acupoint increases interleukin-4 responsiveness in macrophages, generation of alternatively activated macrophages and susceptibility to Leishmania major infection. Chinese Medicine 2012 7:17.Submit your next manuscript to BioMed Central and take full advantage of:?Convenient online submission ?Thorough peer review PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28549975 ?No space constraints or color figure charges ?Immediate publication on acceptance ?Inclusion in PubMed, CAS, Scopus and Google Scholar ?Research which is freely available for redistributionSubmit your manuscript at www.biomedcentral.com/submit
Ruiming et al. BMC Genomics 2010, 11:452 http://www.biomedcentral.com/1471-2164/11/RESEARCH ARTICLEOpen AccessComparative venom gland transcriptome analysis of the scorpion Lychas NilotinibMedChemExpress Nilotinib mucronatus reveals intraspecific toxic gene diversity and new venomous componentsZhao Ruiming, Ma Yibao, He Yawen, Di Zhiyong, Wu Yingliang, Cao Zhijian*, Li Wenxin*AbstractBackground: Lychas mucronatus is one scorpion species widely distributed in Southeast Asia and southern China. Anything is hardly known about its venom components, despite the fact that it can often cause human accidents. In this work, we performed a venomous gland transcriptome analysis by constructing and screening the venom gland cDNA library of the scorpion Lychas mucronatus from Yunnan province and compared it with the previous results of Hainan-sourced Lychas mucronatus. Results: A total of sixteen known types of venom peptides and proteins are obtained from the venom gland cDNA library of Yunnan-sourced Lychas mucronatus, which greatly increase the number of currently reported scorpion venom peptides. Interestingly, we also identified nineteen atypical types of venom molecules seldom reported in scorpion species. Surprisingly, the comparative transcriptome analysis of Yunnan-sourced Lychas mucronatus and Hainan-sourced Lychas mucronatus indicated that enormous diversity and vastly abundant difference could be found in venom peptides and proteins between populations of the scorpion Lychas mucronatus from different geographical regions. Conclusions: This work characterizes PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27488460 a large number of venom molecules never identified in scorpion species. This result provides a comparative analysis of venom transcriptomes of the scorpion Lychas mucronatus from different geographical regions, which thoroughly reveals the fact that the venom peptides and proteins of the same scorpion species from different geographical regions are highly diversified and scorpion evolves to adapt a new environment by altering the primary structure and abundance of venom peptides and proteins.Background More than 400 million years of evolution does not make the scorpions alter their morphology. However, although this one of the oldest arachnid is highly conserved in shape all along, they occupy vast territory of the world from Africa to Asia, Australia and America. Such powerful.