On the chosen species for the total bivalve production in Korea, the place of farms for the provided species along the Korean coastline, the significance in the species in the local and international markets, the availability species on Korean marketplace for the shoppers through the year, and their frequencies of consumption by buyers had been criteria for the selection of species for this study. Among all bivalve species present at the market place, in accordance with the criteria, 3 clams species (Venerupis philippinarum, Anadara broughtonii, and Tegillarca granosa) and two scallops species (Mizuhopecten yessoensis and Argopecten irradians) were chosen. Venerupis philippinarum (Manila clam) is among the 5 most commercially valuable bivalve worldwide [17] due to the fact of its nutritional worth, flavor, and low price. Venerupis philippinarum usually shows higher bioaccumulation values for most metals/metalloids, but its role as a bioindicator continues to be controversial [17]. Mizohopecten yessoensis (Yesso scallop) is an economically significant bivalve species within the aquaculture and fishery in Asian nations [18]. It is very valued by shoppers and is typically consumed fresh. Argopecten irradians (the bay scallop) was initially introduced in the United D-Fructose-6-phosphate disodium salt manufacturer states of america into China in 1982, and it has swiftly turn out to be one of the most important marine cultured bivalves in China [19]. In addition to V. philippinarum and M. yessoensis, Tegillarca granosa (compact blood clam, blood cockle) and Anadara broughtonii (large blood clam, blood cockle) are two of eight species, which the most contributed to bivalve production in Korea. Forty-eight samples (1 to 2 kg per sample) of 5 chosen bivalve species intended for human consumption were purchased from unique fishery markets in Korea during April and Might 2018. Details on the harvest place of these bivalves was obtained from salesmen. Taxonomic ranks, common names, and number of samples for each species are summarized in Table S1 (Supplementary Material).Foods 2021, ten,three ofSample Preparation Immediately after becoming bought, reside animals have been put in the boxes with ice and ��-Conotoxin PIA Autophagy delivered for the laboratory. The total length and weight of every animal have been measured. The entire soft tissue from the shell was removed by the usage of a plastic knife. Composite samples have been prepared applying the tissue samples of minimal ten animals from the same species. All cleaned and separated tissue samples have been cut into pieces and freeze-dried. The dried samples had been then crushed employing mortar and pestle into a powder and further homogenized prior to analyses. Dry samples (1 g) had been weighed to a precision of 0.1 mg and placed directly in 12-mL PTFE tubes. Nitric acid (7 mL) and hydrogen peroxide (1 mL) had been then added and the samples had been digested inside the microwave oven (Speedwave, Berghof, Germany). Digestion was performed as follows: samples had been heated to 50 C and held for ten min at this temperature; next, the temperature was linearly enhanced to 150 C and held for 10 min at this temperature; then, the temperature was then linearly enhanced to 180 C and held at 180 C for 20 min. Right after cooling to room temperature, the digested solutions had been transferred to 25-mL volumetric flasks and diluted in distilled water. Every sample was analyzed in duplicate, and each and every evaluation consisted of three replicates. The mean concentrations of elements (mg/g or /g) within the edible components of your bivalve species had been calculated on the wet weight (WW) of samples (Table 1) using water content information for ea.