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(2022) 16:1 Ho et al. Human Genomics doi.org/10.1186/s40246-021-00374-GENE Family UPDATEOpen AccessUpdate on the keratin gene loved ones: evolution, tissue-specific expression patterns, and relevance to clinical disordersMinh Ho1, Brian Thompson2, Jeffrey Nicholas Fisk3, Daniel W. Nebert4,five, Elspeth A. Bruford6,7, Vasilis Vasiliou2 and 5-HT2 Receptor Agonist Storage & Stability Christopher G. Bunick1,8Abstract Intermediate filament (IntFil) genes arose throughout early metazoan evolution, to supply mechanical assistance for plasma m