Product Name :
Apatinib
Description:
Apatinib, also known as Rivoceranib, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.
CAS:
1218779-75-9
Molecular Weight:
493.58
Formula:
C25H27N5O4S
Chemical Name:
N-[4-(1-cyanocyclopentyl)phenyl]-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide; methanesulfonic acid
Smiles :
CS(O)(=O)=O.{{Fitusiran} medchemexpress|{Fitusiran} Factor Xa|{Fitusiran} Purity & Documentation|{Fitusiran} References|{Fitusiran} manufacturer|{Fitusiran} Cancer} N#CC1(CCCC1)C1=CC=C(C=C1)NC(=O)C1=CC=CN=C1NCC1C=CN=CC=1
InChiKey:
FYJROXRIVQPKRY-UHFFFAOYSA-N
InChi :
InChI=1S/C24H23N5O.{{Sotagliflozin} site|{Sotagliflozin} Membrane Transporter/Ion Channel|{Sotagliflozin} Protocol|{Sotagliflozin} In Vitro|{Sotagliflozin} custom synthesis|{Sotagliflozin} Epigenetic Reader Domain} CH4O3S/c25-17-24(11-1-2-12-24)19-5-7-20(8-6-19)29-23(30)21-4-3-13-27-22(21)28-16-18-9-14-26-15-10-18;1-5(2,3)4/h3-10,13-15H,1-2,11-12,16H2,(H,27,28)(H,29,30);1H3,(H,2,3,4)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Apatinib, also known as Rivoceranib, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities.PMID:24187611 The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.|Product information|CAS Number: 1218779-75-9|Molecular Weight: 493.58|Formula: C25H27N5O4S|Chemical Name: N-[4-(1-cyanocyclopentyl)phenyl]-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide; methanesulfonic acid|Smiles: CS(O)(=O)=O.N#CC1(CCCC1)C1=CC=C(C=C1)NC(=O)C1=CC=CN=C1NCC1C=CN=CC=1|InChiKey: FYJROXRIVQPKRY-UHFFFAOYSA-N|InChi: InChI=1S/C24H23N5O.CH4O3S/c25-17-24(11-1-2-12-24)19-5-7-20(8-6-19)29-23(30)21-4-3-13-27-22(21)28-16-18-9-14-26-15-10-18;1-5(2,3)4/h3-10,13-15H,1-2,11-12,16H2,(H,27,28)(H,29,30);1H3,(H,2,3,4)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|