Product Name :
Indobufen
Description:
Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
CAS:
63610-08-2
Molecular Weight:
295.33
Formula:
C18H17NO3
Chemical Name:
2-[4-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]butanoic acid
Smiles :
CCC(C(O)=O)C1C=CC(=CC=1)N1CC2=CC=CC=C2C1=O
InChiKey:
AYDXAULLCROVIT-UHFFFAOYSA-N
InChi :
InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{4-Octyl itaconate} web|{4-Octyl itaconate} Keap1-Nrf2|{4-Octyl itaconate} TGF-beta/Smad|{4-Octyl itaconate} Protocol|{4-Octyl itaconate} Data Sheet|{4-Octyl itaconate} custom synthesis}
Shelf Life:
≥12 months if stored properly.{{Imatinib} medchemexpress|{Imatinib} c-Kit|{Imatinib} Purity & Documentation|{Imatinib} In Vitro|{Imatinib} manufacturer|{Imatinib} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23008002
Additional information:
Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.|Product information|CAS Number: 63610-08-2|Molecular Weight: 295.33|Formula: C18H17NO3|Chemical Name: 2-[4-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]butanoic acid|Smiles: CCC(C(O)=O)C1C=CC(=CC=1)N1CC2=CC=CC=C2C1=O|InChiKey: AYDXAULLCROVIT-UHFFFAOYSA-N|InChi: InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (846.51 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. Indobufen inhibits TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen reduces the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered.|Products are for research use only. Not for human use.|