Product Name :
Remdesivir
Description:
Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.
CAS:
1809249-37-3
Molecular Weight:
601.57
Formula:
C27H34N6O8P
Chemical Name:
2-ethylbutyl((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Smiles :
C[C@@H](C([O-])=O)N(CC(CC)CC)[P@@](=O)(OC1C=CC=CC=1)OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)C1=CC=C2C(N)=NC=NN12
InChiKey:
KFHKFHCTNJBRGF-YSOARWBDSA-M
InChi :
InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-32(17(3)26(36)37)42(38,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,36,37)(H2,29,30,31)/p-1/t17-,21+,23+,24+,27-,42-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Abagovomab} MedChemExpress|{Abagovomab} Biological Activity|{Abagovomab} In Vitro|{Abagovomab} custom synthesis|{Abagovomab} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Amygdalin} site|{Amygdalin} Protocol|{Amygdalin} References|{Amygdalin} manufacturer|{Amygdalin} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:26780211
Additional information:
Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.|Product information|CAS Number: 1809249-37-3|Molecular Weight: 601.57|Formula: C27H34N6O8P|Synonym:|GS-5734|GS5734|Prodrug of GS-441524|Remdesivir|GS 5734|Prodrug of GS441524|Chemical Name: 2-ethylbutyl((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate|Smiles: C[C@@H](C([O-])=O)N(CC(CC)CC)[P@@](=O)(OC1C=CC=CC=1)OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)C1=CC=C2C(N)=NC=NN12|InChiKey: KFHKFHCTNJBRGF-YSOARWBDSA-M|InChi: InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-32(17(3)26(36)37)42(38,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,36,37)(H2,29,30,31)/p-1/t17-,21+,23+,24+,27-,42-/m0/s1|Technical Data|Appearance: Solid Power.|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|How to use|In Vitro:|Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h.|References:|Xie M, Chen Q. Insight into 2019 novel coronavirus – an updated intrim review and lessons from SARS-CoV and MERS-CoV. Int J Infect Dis. 2020 Apr 1. doi: 10.1016/j.ijid.2020.03.071. Epub ahead of print. PMID: 32247050; PMCID: PMC7118633.Products are for research use only. Not for human use.|