Product Name : BelizatinibDescription:Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase.CAS: 1357920-84-3Molecular Weight:577.73Formula: C33H44FN5O3Chemical Name:…
Product Name : SalbutamolDescription:Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).CAS: 18559-94-9Molecular Weight:239.31Formula: C13H21NO3Chemical…
Product Name : BQ-123Description:BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation…
Product Name : HA155Description:HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC50 of 5.7 nM.CAS: 1312201-00-5Molecular Weight:463.29Formula: C24H19BFNO5SChemical Name: {4--2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)methyl]phenyl}boronic acidSmiles : OB(O)C1C=CC(COC2C=CC(/C=C3\SC(=O)N(CC4C=CC(F)=CC=4)C\3=O)=CC=2)=CC=1InChiKey: BRWUZCBSWABPMR-XKZIYDEJSA-NInChi : InChI=1S/C24H19BFNO5S/c26-20-9-3-17(4-10-20)14-27-23(28)22(33-24(27)29)13-16-5-11-21(12-6-16)32-15-18-1-7-19(8-2-18)25(30)31/h1-13,30-31H,14-15H2/b22-13-Purity: ≥98%…
Product Name : Org37684Description:Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5…
Product Name : ORL1 antagonist 1Description:ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM.CAS: 1174985-59-1Molecular Weight:367.88Formula: C20H22ClN5Chemical Name: N-{methyl}cyclopentanamineSmiles : CC1=C(C2C=NC=CC=2)N(N=C1CNC1CCCC1)C1=NC=CC=C1ClInChiKey: GZENXSQONSXYLR-UHFFFAOYSA-NInChi :…
Product Name : THZ531Description:THZ531 is a selective and covalent inhibitor of both CDK12 and CDK13 with IC50s of 158 nM and 69 nM, respectively.CAS: 1702809-17-3Molecular Weight:558.07Formula: C30H32ClN7O2Chemical Name: (2E)-N-{4-amino}piperidine-1-carbonyl]phenyl}-4-(dimethylamino)but-2-enamideSmiles :…
Product Name : ZidebactamDescription:Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.CAS: 1436861-97-0Molecular Weight:391.40Formula: C13H21N5O7SChemical Name: formohydrazido}carbonyl)-1,6-diazabicyclooctan-6-yl]oxidanesulfonic acidSmiles…
Product Name : (S)-MapracoratDescription:(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist.CAS: 887375-15-7Molecular Weight:462.48Formula: C25H26F4N2O2Chemical Name: (2S)-4-(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)-4-methyl-1--2-(trifluoromethyl)pentan-2-olSmiles : CC(C)(C(O)(CNC1C=CC=C2N=C(C)C=CC=12)C(F)(F)F)C1C=C(F)C=C2CCOC2=1InChiKey: VJGFOYBQOIPQFY-DEOSSOPVSA-NInChi : InChI=1S/C25H26F4N2O2/c1-15-7-8-18-20(5-4-6-21(18)31-15)30-14-24(32,25(27,28)29)13-23(2,3)19-12-17(26)11-16-9-10-33-22(16)19/h4-8,11-12,30,32H,9-10,13-14H2,1-3H3/t24-/m0/s1Purity: ≥98% (or refer to the Certificate of…
Product Name : AR-A 2Description:AR-A 2 is a selective 5-HT1B receptor antagonist, with high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki=0.24 and 0.47 nM)…