Product Name :
Zidebactam
Description:
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.
CAS:
1436861-97-0
Molecular Weight:
391.40
Formula:
C13H21N5O7S
Chemical Name:
[(1R,2S,5R)-7-oxo-2-({[(3R)-piperidin-3-yl]formohydrazido}carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid
Smiles :
OS(=O)(=O)ON1[C@H]2C[N@]([C@@H](CC2)C(=O)NNC(=O)[C@H]2CNCCC2)C1=O
InChiKey:
YCZPXRQPDCXTIO-BBBLOLIVSA-N
InChi :
InChI=1S/C13H21N5O7S/c19-11(8-2-1-5-14-6-8)15-16-12(20)10-4-3-9-7-17(10)13(21)18(9)25-26(22,23)24/h8-10,14H,1-7H2,(H,15,19)(H,16,20)(H,22,23,24)/t8-,9-,10+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Daprodustat} MedChemExpress|{Daprodustat} HIF/HIF Prolyl-Hydroxylase|{Daprodustat} Purity & Documentation|{Daprodustat} Formula|{Daprodustat} manufacturer|{Daprodustat} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Lixisenatide} medchemexpress|{Lixisenatide} JNK|{Lixisenatide} Purity & Documentation|{Lixisenatide} References|{Lixisenatide} supplier|{Lixisenatide} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:29844565
Additional information:
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.|Product information|CAS Number: 1436861-97-0|Molecular Weight: 391.40|Formula: C13H21N5O7S|Chemical Name: [(1R,2S,5R)-7-oxo-2-({[(3R)-piperidin-3-yl]formohydrazido}carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid|Smiles: OS(=O)(=O)ON1[C@H]2C[N@]([C@@H](CC2)C(=O)NNC(=O)[C@H]2CNCCC2)C1=O|InChiKey: YCZPXRQPDCXTIO-BBBLOLIVSA-N|InChi: InChI=1S/C13H21N5O7S/c19-11(8-2-1-5-14-6-8)15-16-12(20)10-4-3-9-7-17(10)13(21)18(9)25-26(22,23)24/h8-10,14H,1-7H2,(H,15,19)(H,16,20)(H,22,23,24)/t8-,9-,10+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (638.73 mM; Need ultrasonic). H2O : 50 mg/mL (127.75 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Zidebactam (WCK-5107) inhibits WT Enterobacteriaceae with a MIC50 of 0.25 mg/L. Zidebactam alone exhibits variable activity when tested against E. coli (MIC50/90 0.12/0.12 mg/L) and Enterobacter spp. (MIC50/90 0.12/0.25 mg/L).|Products are for research use only. Not for human use.|