Product Name :
HA155
Description:
HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC50 of 5.7 nM.
CAS:
1312201-00-5
Molecular Weight:
463.29
Formula:
C24H19BFNO5S
Chemical Name:
{4-[(4-{[(5Z)-3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)methyl]phenyl}boronic acid
Smiles :
OB(O)C1C=CC(COC2C=CC(/C=C3\SC(=O)N(CC4C=CC(F)=CC=4)C\3=O)=CC=2)=CC=1
InChiKey:
BRWUZCBSWABPMR-XKZIYDEJSA-N
InChi :
InChI=1S/C24H19BFNO5S/c26-20-9-3-17(4-10-20)14-27-23(28)22(33-24(27)29)13-16-5-11-21(12-6-16)32-15-18-1-7-19(8-2-18)25(30)31/h1-13,30-31H,14-15H2/b22-13-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC50 of 5.7 nM.|Product information|CAS Number: 1312201-00-5|Molecular Weight: 463.29|Formula: C24H19BFNO5S|Chemical Name: {4-[(4-{[(5Z)-3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)methyl]phenyl}boronic acid|Smiles: OB(O)C1C=CC(COC2C=CC(/C=C3\SC(=O)N(CC4C=CC(F)=CC=4)C\3=O)=CC=2)=CC=1|InChiKey: BRWUZCBSWABPMR-XKZIYDEJSA-N|InChi: InChI=1S/C24H19BFNO5S/c26-20-9-3-17(4-10-20)14-27-23(28)22(33-24(27)29)13-16-5-11-21(12-6-16)32-15-18-1-7-19(8-2-18)25(30)31/h1-13,30-31H,14-15H2/b22-13-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Xanthohumol} medchemexpress|{Xanthohumol} COX|{Xanthohumol} Technical Information|{Xanthohumol} In stock|{Xanthohumol} supplier|{Xanthohumol} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Genistein} medchemexpress|{Genistein} Autophagy|{Genistein} Purity & Documentation|{Genistein} Description|{Genistein} supplier|{Genistein} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24428212 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|HA-155 inhibits ATX by binding to the ATX active site. HA155 completely attenuates the thrombin-mediated increase in platelet-derived LPA in a dose-dependent manner.|Products are for research use only. Not for human use.|