Product Name :
Biotin-PEG5-azide
Description:
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
CAS:
1163732-89-5
Molecular Weight:
532.65
Formula:
C22H40N6O7S
Chemical Name:
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(17-azido-3,6,9,12,15-pentaoxaheptadecan-1-yl)pentanamide
Smiles :
[N-]=[N+]=NCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21
InChiKey:
MKXKDMBFPMTVAW-ZJOUEHCJSA-N
InChi :
InChI=1S/C22H40N6O7S/c23-28-25-6-8-32-10-12-34-14-16-35-15-13-33-11-9-31-7-5-24-20(29)4-2-1-3-19-21-18(17-36-19)26-22(30)27-21/h18-19,21H,1-17H2,(H,24,29)(H2,26,27,30)/t18-,19-,21-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Cyclopamine} MedChemExpress|{Cyclopamine} Endogenous Metabolite|{Cyclopamine} Biological Activity|{Cyclopamine} References|{Cyclopamine} manufacturer|{Cyclopamine} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Pentoxifylline} site|{Pentoxifylline} Autophagy|{Pentoxifylline} Biological Activity|{Pentoxifylline} References|{Pentoxifylline} manufacturer|{Pentoxifylline} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35954127
Additional information:
Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.|Product information|CAS Number: 1163732-89-5|Molecular Weight: 532.65|Formula: C22H40N6O7S|Chemical Name: 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(17-azido-3,6,9,12,15-pentaoxaheptadecan-1-yl)pentanamide|Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21|InChiKey: MKXKDMBFPMTVAW-ZJOUEHCJSA-N|InChi: InChI=1S/C22H40N6O7S/c23-28-25-6-8-32-10-12-34-14-16-35-15-13-33-11-9-31-7-5-24-20(29)4-2-1-3-19-21-18(17-36-19)26-22(30)27-21/h18-19,21H,1-17H2,(H,24,29)(H2,26,27,30)/t18-,19-,21-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|