Product Name :
Semaxanib (SU5416)
CAS No.:
194413-58-6
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC1=CC(=C([NH]1)/C=C/2C(=O)NC3=CC=CC=C23)C
Product Description :
Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR.{{1957203-01-8} site|{1957203-01-8} Biological Activity|{1957203-01-8} In stock|{1957203-01-8} manufacturer} Phase 3.
Formula:
C15H14N2O
Molecular Weight :
238.28
Synonyms:
Additional Information:
|CAS No. 194413-58-6 ; |Formula C15H14N2O ; |Molecular Weight 238.28 ; |SMILES CC1=CC(=C([NH]1)/C=C/2C(=O)NC3=CC=CC=C23)C ; |Target VEGFR ; |Product Description Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.{{1923833-60-6} site|{1923833-60-6} Protocol|{1923833-60-6} Data Sheet|{1923833-60-6} manufacturer} 23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR.PMID:29261911 Phase 3. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO