Product Name :
Anti-SORT1, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-SORT1, Human antibody is designed for detecting human SORT1 specifically. Based on ELISA and/or FCM, Anti-SORT1, Human antibody reacts with human SORT1 specifically. | Immunogen: Recombinant human SORT1 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human SORT1 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB).{{2755890-53-8} medchemexpress|{2755890-53-8} Protocol|{2755890-53-8} In Vitro|{2755890-53-8} custom synthesis} Also, Sortilin acts as a receptor for neurotensin.{{1513857-77-6} web|{1513857-77-6} Technical Information|{1513857-77-6} In Vitro|{1513857-77-6} manufacturer}
Description2 :
Anti-SORT1, Human antibody is designed for detecting human SORT1 specifically.PMID:30969670 Based on ELISA and/or FCM, Anti-SORT1, Human antibody reacts with human SORT1 specifically.
Immunogen:
Recombinant human SORT1
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.